Derek and Addison after agreed to bring its relationships various other try in addition they put aside its relationship

Addison Forbes Montgomery [ ]

Derek and Addison satisfied at scientific university. It become dating and you will were elizabeth a very very acknowledged doc within her specialty and you may worked inside the a private routine, exactly like Derek additionally the a few existed together with her inside New york. They certainly were comfy economic and you may possessed a house about Hamptons.

Yet not, after a while they expanded aside. They certainly were both expenses much time establishing right up its lives that are professional, having Derek later saying he was never around for their and that they was indeed psychologically distant in their private lifestyle. The worries contributed Addison in order to cheating which have Derek’s closest friend, Mark Sloan. Derek receive them and you can transferred to Seattle.

Addison discover Derek two months after. She approved work in one medical and you may try assured they might make an effort to help save their marriage out-of 11 age. The girl coming amazed Derek and his wife, Meredith Grey, once the she hadn’t identified Derek are married.

As time passes, Addison realized one to Derek is now in love with Meredith and you will you to she had messed up the relationships beyond repair whenever she slept which have Mark. It later on agreed to breakup and you may stayed loved ones. Derek visited their from the this lady this new individual behavior in the La and you will she need him really together with the brand new matchmaking. It is not familiar just how she coped which have Derek’s demise.

Draw Sloan [ ]

Draw and you may Derek were close friends given that youth. ily history and you may was welcomed to the Shepherd members of the family given that a good 2nd kid. It went along to scientific school along with her. not, during the 2005, Derek located Addison cheat which have Draw. The guy departed Ny whenever they were reunited following the Mark’s coming at health the guy spent some time working within, the guy punched Mark. Draw is at a healthcare facility so you’re able to reconcile with Addison, and that fell as a result of.

Mark’s acceptance of a career in the hospital he worked at the because Lead away from Cosmetic surgery, resentful Derek, but they remained professional and arrive at make a relationship once more. It afterwards found myself in a fight whenever Derek revealed one to Draw are looking for Lexie Grey, their young sister in law. He desired Derek to go away this lady by yourself and escort Westminster you will try upset one to he had not.

Over the years, Derek visited see how a good Mark and Lexie was indeed together with her, incase Mark confided from inside the your you to Lexie told him she had been in love with your, Derek advised e means. Derek is troubled when Draw passed away, and try from the his front side because the his life support machine is actually prevented.

Amelia Shepherd [ ]

Derek try closest so you can his youngest cousin, Amelia. It shared the newest despair regarding seeing their father feel sample to death and this understandably got a powerful connect with on them. They became estranged because Amelia coped on losses if you take medication. Derek discover the lady cold whenever she stole his medication mat so you’re able to access drugs and grabbed an overdose. Derek saved her life nonetheless they drifted apart consequently regarding their strategies.

These people were reunited when she heard that Derek is actually try of the Gary Clark. Derek are unhappy and you may attempted to force this lady out. The guy offered the reason because their previous knowledge of drugs. not, they afterwards had a discussion where it shared the aches about their dad’s passing, and he achieved an insight into as to the reasons she took place the new station she did. He informed he attempted to mask his pain regarding her in addition to their father as he desired to protect their from sharing their problems. It reconnected and turned into closer.

Although not, by their next reunion, Amelia had relapsed and you may went back to treatment. Amelia wanted Derek to simply help the woman towards the question of Erica Warner who had a head tumour. Derek pushed her aside again and you can made an effort to convince this lady to help you get off possible by yourself as he informed this lady the fresh new tumour are impossible to get rid of. She neglected your and then he offered to assist their as he realized she would never ever give-up.